The EU was slow in responding to the recent developments in the Middle East. It was even criticized for lacking a strategy toward the countries affected by the Arab Spring. Furthermore, the EU sent contradictory signals regarding the democratic transitions and political reforms. Still, it is not clear if it is supporting stability or change. Meanwhile, Turkish foreign policy became more active and assertive searching for a leadership role in the Middle East. Yet, this approach has raised a critical question: whether Turkey follows an autonomous foreign policy from the West, namely the US and the EU, in other words the “losing Turkey” debate. Trying to elaborate on this debate, the article analyzes Turkey and the EU foreign policies towards the Middle East in the context of the Arab Spring with a particular emphasis on the cases of Egypt, Iran, and Syria. These three cases are chosen for two reasons.