Israel’s aid initiatives have historically been facilitated through the Agency for International Development Cooperation (MASHAV). However, the COVID-19 pandemic impacted MASHAV’s ability to provide assistance due to budget cuts and government instability. As such, Israel’s COVID-19 diplomacy initiative took on greater importance in maintaining its presence and reputation internationally. This article analyzes Israel’s approach to COVID-19 diplomacy, which involved providing medical teams, PPE, and surplus vaccines to approximately 20 countries, and examines the political and strategic calculations behind Israel’s decision to extend assistance to specific countries. The article argues that Israel’s COVID-19 diplomacy initiative was more limited in scope and geography compared to other countries with similar economic development levels, and aid efforts were concentrated in regions where Israel has sought to increase its involvement in recent years, particularly sub-Saharan Africa and Central Europe. Finally, the article assesses the impact of Israel’s COVID-19 diplomacy initiative on its diplomatic relations with recipient countries and the broader international community.