Since the early 1970s, member states of the Organisation of the Islamic Conference (OIC) have been pursuing the goal of enhancing economic and commercial cooperation to improve the economic linkages and coordination among themselves and to jointly act against the global challenges facing them. Special attention has been given to trade and considerable efforts have been exerted at various OIC forums to develop ways and means of joint cooperative action to increase trade among the OIC countries. Enhancing intra-OIC trade was also among the priorities of the Ten-Year Programme of Action, which set a target of a level of 20 percent for intra-OIC trade to be achieved during the period covered by the Programme (by 2015). It is with this inspiration that this study presents an analytical overview of the evolution and the current structure of the merchandise trade among the OIC countries. Also, broad policy recommendations are outlined to enhance intra-OIC trade.