The shifts in U.S. foreign policy toward the Palestinian cause reveal the fact that this policy varies from one period to another, and from one president to another, and that its role and its impact on the conflict contribute greatly to the progress of the peace process. The region has witnessed increased tension since America made the Palestinian cause its second priority. Whether its involvement is active or not, the U.S. role remains strong and influential in achieving peace and spreading security and stability in the Middle East. The essay concludes with recommendations for concluding the long-standing conflict.